Journal: Journal of medical systems

Article Title: Predicting Major Adverse Kidney Events among Critically Adults Using the Electronic Health Record

doi: 10.1007/s10916-017-0806-4

Figure Lengend Snippet: Bootstrap overfitting-corrected calibration curve estimate for the MAKE30 logistic model.

Article Snippet: The odds ratio (OR) for risk factors in the model are summarized in and plotted in Appendix D . For the full equation of the model, see Appendix E . fig ft0 fig mode=article f1 fig/graphic|fig/alternatives/graphic mode="anchored" m1 Open in a separate window caption a7 caption a8 Receiver-Operator Curve of the MAKE30 Prediction Model After bootstrap correction for overfitting, AUC was 0.903. fig ft0 fig mode=article f1 fig/graphic|fig/alternatives/graphic mode="anchored" m1 Open in a separate window caption a7 caption a8 Bootstrap-Validated Calibration Curve of MAKE30 Prediction Model Bootstrap overfitting-corrected calibration curve estimate for the MAKE30 logistic model. table ft1 table-wrap mode="anchored" t5 caption a7 Odds Ratio (95% CI) Chi-Square Degrees of Freedom P-value Age (years) (68.43:43.55) 1.16 (1.04, 1.31) 8.57 2 0.014 UHC Expected Mortality (0.05:0) 2.32 (2.06, 2.61) 921.22 2 <0.001 Baseline Creatinine (1.08:0.74) 0.68 (0.6, 0.76) 82.12 2 <0.001 Fluid Receipt 24 hours prior to ICU admission (Liters) (1.8:0) 1.03 (0.9, 1.17) 0.13 1 0.706 Race (Other:White) 1.07 (0.9, 1.29) 0.61 1 0.433 Gender (Female:Male) 0.84 (0.72, 0.98) 4.95 1 0.026 Admitting Service 25.13 9 0.003 Pulmonary:Trauma 1.07 (0.63, 1.82) Cardiology:Trauma 1.18 (0.65, 2.14) Cardiovascular Surgery:Trauma 0.89 (0.48, 1.65) Neurosurgery:Trauma 0.45 (0.21, 0.99) Neurology:Trauma 0.79 (0.39, 1.62) Internal Medicine:Trauma 1.35 (0.82, 2.2) General Surgery:Trauma 1.76 (1.06, 2.93) Surgical Subspecialty:Trauma 1.24 (0.7, 2.22) Obstetrics:Trauma 1.4 (0.53, 3.72) Unit 7.05 4 0.133 Cardiovascular ICU:Medical ICU 0.86 (0.58, 1.29) Neurological ICU:Medical ICU 1.35 (0.8, 2.29) Trauma ICU:Medical ICU 1.06 (0.64, 1.77) Surgical ICU:Medical ICU 0.73 (0.52, 1.02) Source of Admission 104.24 4 <0.001 Operating Room:Emergency Department 0.73 (0.55, 0.98) Transfer from another Hospital:Emergency Department 1.47 (1.19, 1.82) Hospital Ward:Emergency Department 2.69 (2.11, 3.42) Other:Emergency Department 1.06 (0.74, 1.51) Mechanical Ventilation within 24 hours of ICU admission 1.59 (1.34, 1.89) 27.69 1 <0.001 Vasopressors within 24 hours of ICU admission 1.46 (1.23, 1.74) 18.83 1 <0.001 Renal Replacement Therapy prior to ICU admission 0.07 (0.05, 0.1) 171.84 1 <0.001 Acute Kidney Injury at ICU admission 4.98 (4.12, 6.03) 273.02 1 <0.001 Chronic Kidney Disease 1.2 (0.95, 1.51) 2.3 1 0.13 Elixhauser Renal Failure a 3.22 (2.64, 3.94) 130.37 1 <0.001 Open in a separate window Abbreviations: UHC, University Health System Consortium; ICU, intensive care unit; a Elixhauser Renal Failure from reference 17 Data are presented as median [25 th percentile; 75 th percentile] or percentage (number).

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